http://www.nature.com/news/2009/090429/pdf/4581091a.pdf
"The difference between 350 and 450 is not just one of degree. It’s one of direction. A CO2 concentration of 450 p.p.m. awaits the world at some point in the future that might conceivably, though with difficulty, be averted. But 350 p.p.m. can be seen only in the rear view mirror. Hansen believes that CO2 levels already exceed those that would provide longterm safety, and the world needs not just to stop but to reverse course. "
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